Ocoee, Florida · Independent Practice
Endocrine care that focuses on you.
A privately owned endocrinology practice in Ocoee, Florida, treating adults with diabetes, thyroid, adrenal and metabolic conditions — with an ICH-GCP certified research center on site.
Where We Focus
Root-cause endocrine care, built around you.
Classical internal medicine expertise, paired with advanced subspecialty care, to restore your metabolic health.
Diabetes Management
Continuous glucose monitoring, insulin pump therapy, custom insulin regimens, and the latest FDA-approved Type 2 treatments — GLP-1, dual GIP/GLP-1 and SGLT2 agents.
Thyroid & Parathyroid
Diagnosis and treatment of hypothyroidism, Hashimoto's, Graves' disease, thyroid nodules, and hyperparathyroidism.
Medical Weight Loss
Root-cause metabolic evaluation and custom GLP-1/GIP protocols under ongoing physician supervision, including fatty liver disease (NASH/MASH).
Specialized Endocrine Disorders
Diagnosis and management of pituitary conditions, acromegaly, Cushing's syndrome, adrenal insufficiency, hypogonadism, PCOS/PMOS, and calcium and parathyroid disorders.
West Orange Endocrinology Research Center
Clinical research, explained plainly.
We bridge FDA-approved and sponsored clinical research investigations that provide options for patients who qualify for these trials. If you qualify, you will receive close clinical oversight and may receive a small stipend for your participation.
Multi-receptor incretin therapies
GIP/GLP-1/glucagon agonists and oral GLP-1 formulations under active investigation.
Once-weekly basal insulins
Dual-action metabolic agents and novel oral medications for Type 1 and Type 2 diabetes.
Kidney-sparing therapies
Breakthrough treatments targeting diabetic kidney disease and CKD progression.
Targeted biologic therapies
Novel treatments under investigation for Graves' disease and hypothyroidism.
Research Partnerships
Sponsors & CROs
An ICH-GCP certified site in Central Florida with a dedicated research team and a fully equipped facility. Feasibility questionnaires and protocol synopses are exchanged under a mutual confidentiality agreement — get in touch and we will start there.
Request a Confidentiality Agreement →Health Library
Straight answers, written by the physicians who treat you.
No syndicated content, no filler — every article is authored or medically reviewed by our own clinicians, and carries a named author and a review date.
Beyond the Daily Spike: What Continuous Glucose Monitors Actually Teach Us About Metabolism
What a CGM can and cannot tell you: why sensor readings lag your blood, what a compression low is, and how to read the trend instead of the number.
Understanding Obesity: Diagnosis, Health Risks, and Related Conditions
Obesity is a chronic condition, not a personal failure. What BMI does and does not tell you, the conditions linked to it, and what to ask your provider.
Demystifying Calories & Body Recomposition
Why crash dieting costs you muscle, what your metabolism actually spends energy on, and how to lose fat without wrecking your baseline metabolic rate.
Written in plain language by our team — never AI-generated filler.
Browse All Articles →Who's Behind the Science
The clinicians behind the research.
Jose M. Mandry, MD
Three decades of endocrine care in Central Florida. Trained in Internal Medicine at St. Vincent's Medical Center (Yale affiliate) and Endocrinology & Metabolism at Roger Williams / Rhode Island Hospital (Brown affiliate).
Maria del Carmen Freire, PA-C
MPAS from Florida International University; BS in Cell and Molecular Biology from USF. Focused on individualized diabetes management, hormone balancing, and weight-loss optimization.
Maria Ines Marulanda, MD
Three decades as an internist, medical director, and Principal Investigator in Venezuela, now directing site operations across the practice's Phase II–IV research portfolio in Ocoee.
Ineska Freire, MD, CRC
Clinical research coordinator with the practice since 2017, supporting 20+ industry trials spanning diabetes, obesity, kidney disease, and autoimmune disease.
Let's Talk
Ready when you are.
Address
Ocoee, FL 34761
Phone
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Research Team
Fax
Existing Patients
New Patients & Trial Participants Welcome
Accepting new patients.
Most insurances accepted. Call the office or send us a message to schedule a visit.